› 5gu7

X-ray diffraction
2.05Å resolution

Crystal Structure of human ERp44 form II

Released:
DOI: 10.2210/pdb5gu7/pdb
PDB entry 5gu7 coloured by chain, front view.
PDB entry 5gu7 coloured by chain, side view.
PDB entry 5gu7 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER-Golgi interface.
Watanabe S, Harayama M, Kanemura S, Sitia R, Inaba K
Proc Natl Acad Sci U S A 114 E3224-E3232 (2017)
PMID: 28373561

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-189699 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endoplasmic reticulum resident protein 44 Chain: C
Molecule details ›
Chain: C
Length: 396 amino acids
Theoretical weight: 45.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BS26 (Residues: 30-402; Coverage: 99%)
Gene names: ERP44, KIAA0573, TXNDC4, UNQ532/PRO1075
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU
Spacegroup: P3121
Unit cell:
a: 84.15Å b: 84.15Å c: 133.18Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.202 0.2 0.235
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Chemistry and Enzymology of Disulfide Cross-Linking in Proteins.
Fass et al. (2018)
3 more

2 mentions without citation

Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER-Golgi interface.
Watanabe et al. (2017)
1 more