› 5h10

X-ray diffraction
3.2Å resolution

TRAF1-TANk complex

Released:
DOI: 10.2210/pdb5h10/pdb
PDB entry 5h10 coloured by chain, front view.
PDB entry 5h10 coloured by chain, side view.
PDB entry 5h10 coloured by chain, top view.
Source organisms:
Entry authors: Kim CM, Park HH

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171522 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
TNF receptor-associated factor 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 205 amino acids
Theoretical weight: 23.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpARG4
UniProt:
  • Canonical: Q13077 (Residues: 220-416; Coverage: 47%)
Gene names: EBI6, TRAF1
Sequence domains:
Structure domains: Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A
TRAF family member-associated NF-kappa-B activator Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 8 amino acids
Theoretical weight: 862 Da
Source organism: Peptide display vector fth1
Expression system: Not provided
UniProt:
  • Canonical: Q92844 (Residues: 178-185; Coverage: 2%)
Gene names: ITRAF, TANK, TRAF2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P212121
Unit cell:
a: 77.21Å b: 79.034Å c: 113.38Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.218 0.27
Expression systems:
  • Escherichia coli-Pichia pastoris shuttle vector pPpARG4
  • Not provided

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