5hm1

X-ray diffraction
2.96Å resolution

Llama VHH 2E7 in complex with gp41

Released:
Source organisms:
Entry authors: Hock M, Caillat C, Haffke M, Weissenhorn W

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-209062 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
lama VHH antibody 2E7 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 119 amino acids
Theoretical weight: 12.81 KDa
Source organism: Lama glama
Expression system: Escherichia coli
Transmembrane protein gp41 Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 15 amino acids
Theoretical weight: 1.83 KDa
Source organism: HIV-1 M:B_HXB2R
Expression system: Not provided
UniProt:
  • Canonical: P04578 (Residues: 582-596; Coverage: 2%)
Gene name: env

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Unit cell:
a: 37.95Å b: 121.26Å c: 132.21Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.194 0.249
Expression systems:
  • Escherichia coli
  • Not provided