› 5huz

Solution NMR

Solution structure of coiled coil domain of myosin binding subunit of myosin light chain phosphatase

Released:
DOI: 10.2210/pdb5huz/pdb
PDB entry 5huz coloured by chain, ensemble of 20 models, front view.
PDB entry 5huz coloured by chain, ensemble of 20 models, side view.
PDB entry 5huz coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Sharma AK, Birrane G, Anklin C, Rigby AC, Pollak M, Alper SL

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127245 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein phosphatase 1 regulatory subunit 12A Chains: A, B
Molecule details ›
Chains: A, B
Length: 48 amino acids
Theoretical weight: 5.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O14974 (Residues: 931-978; Coverage: 5%)
Gene names: MBS, MYPT1, PPP1R12A
Sequence domains: cGMP-dependent protein kinase interacting domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 45%
Refinement method: torsion angle dynamics, molecular dynamics
Expression system: Escherichia coli BL21

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