Function and Biology Details
Reaction catalysed:
Selective cleavage of Arg-|-Ala and Arg-|-Val bonds in factor IX to form factor IXa.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Coagulation factor XIa complex and Bradykinin (preferred)
PDBe Complex ID:
PDB-CPX-133900 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Coagulation factor XI
Molecule details ›
Chain: A
Length: 607 amino acids
Theoretical weight: 68.12 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Structure domains:
Length: 607 amino acids
Theoretical weight: 68.12 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical:
P03951 (Residues: 19-625; Coverage: 100%)
Sequence domains:
Structure domains:
Kininogen-1 light chain
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 904 Da
Source organism: Homo sapiens
Expression system: synthetic construct
UniProt:
Length: 8 amino acids
Theoretical weight: 904 Da
Source organism: Homo sapiens
Expression system: synthetic construct
UniProt:
- Canonical: P01042 (Residues: 601-608; Coverage: 1%)
