› 5i7p

X-ray diffraction
2Å resolution

Crystal structure of Fkbp12-IF(SlyD), a chimeric protein of human Fkbp12 and the insert in flap domain of Ecoli SlyD

Released:
DOI: 10.2210/pdb5i7p/pdb
PDB entry 5i7p coloured by chain, front view.
PDB entry 5i7p coloured by chain, side view.
PDB entry 5i7p coloured by chain, top view.
Source organisms:
Entry authors: Jakob RP, Knappe TA, Dobbek H, Schmid FX

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141893 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD; Peptidyl-prolyl cis-trans isomerase FKBP1A Chain: A
Molecule details ›
Chain: A
Length: 161 amino acids
Theoretical weight: 18.11 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P62942 (Residues: 2-84; Coverage: 77%)
  • Canonical: P0A9K9 (Residues: 70-139; Coverage: 36%)
Gene names: FKBP1, FKBP12, FKBP1A, JW3311, b3349, slyD
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR591
Spacegroup: P41212
Unit cell:
a: 60.219Å b: 60.219Å c: 120.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.219 0.248
Expression system: Escherichia coli BL21(DE3)

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