› 5i7q

X-ray diffraction
1.9Å resolution

Crystal structure of Fkbp12-IF(SlpA), a chimeric protein of human Fkbp12 and the insert in flap domain of Ecoli SlpA

Released:
DOI: 10.2210/pdb5i7q/pdb
PDB entry 5i7q coloured by chain, front view.
PDB entry 5i7q coloured by chain, side view.
PDB entry 5i7q coloured by chain, top view.
Source organisms:
Entry authors: Jakob RP, Dobbek H, Schmid FX

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142476 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP1A Chain: A
Molecule details ›
Chain: A
Length: 162 amino acids
Theoretical weight: 18.12 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P62942 (Residues: 2-84; Coverage: 77%)
  • Canonical: P0AEM0 (Residues: 73-144; Coverage: 48%)
Gene names: FKBP1, FKBP12, FKBP1A, JW0026, b0028, fkpB, slpA, yaaD
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR591
Spacegroup: P21212
Unit cell:
a: 54.84Å b: 63.61Å c: 46.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.203 0.238
Expression system: Escherichia coli BL21(DE3)

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