› 5ihb

X-ray diffraction
2.24Å resolution

Structure of the immune receptor CD33

Released:
DOI: 10.2210/pdb5ihb/pdb
PDB entry 5ihb coloured by chain, front view.
PDB entry 5ihb coloured by chain, side view.
PDB entry 5ihb coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Dodd RB

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148858 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myeloid cell surface antigen CD33 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 224 amino acids
Theoretical weight: 25.05 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P20138 (Residues: 21-232; Coverage: 61%)
Gene names: CD33, SIGLEC3
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand NAG 12 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P212121
Unit cell:
a: 64.96Å b: 127.04Å c: 143.04Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.236
Expression system: Homo sapiens

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