› 5iw3

X-ray diffraction
2.05Å resolution

anti-CD20 monoclonal antibody Fc fragment

Released:
DOI: 10.2210/pdb5iw3/pdb
PDB entry 5iw3 coloured by chain, front view.
PDB entry 5iw3 coloured by chain, side view.
PDB entry 5iw3 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tang C, Chen Z

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134849 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Immunoglobulin heavy constant gamma 1 Chain: A
Molecule details ›
Chain: A
Length: 208 amino acids
Theoretical weight: 23.64 KDa
Source organism: Homo sapiens
Expression system: Bos taurus
UniProt:
  • Canonical: P01857 (Residues: 119-326; Coverage: 52%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN, GAL
Carbohydrate polymer
2 bound ligands:
Ligand SO4 3 x SO4
Ligand ACT 2 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2221
Unit cell:
a: 64.158Å b: 143.096Å c: 56.556Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.189 0.207
Expression system: Bos taurus

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