› 5j1h

X-ray diffraction
2.8Å resolution

Structure of the spectrin repeats 5 and 6 of the plakin domain of plectin

Released:
DOI: 10.2210/pdb5j1h/pdb
PDB entry 5j1h coloured by chain, front view.
PDB entry 5j1h coloured by chain, side view.
PDB entry 5j1h coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The Structure of the Plakin Domain of Plectin Reveals an Extended Rod-like Shape.
Ortega E, Manso JA, Buey RM, Carballido AM, Carabias A, Sonnenberg A, de Pereda JM
J Biol Chem 291 18643-62 (2016)
PMID: 27413182

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172226 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plectin Chains: A, B
Molecule details ›
Chains: A, B
Length: 196 amino acids
Theoretical weight: 22.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15149 (Residues: 860-928, 999-1116; Coverage: 4%)
Gene names: PLEC, PLEC1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: R3
Unit cell:
a: 178.14Å b: 178.14Å c: 50.68Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.225 0.223 0.269
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

The spectraplakins of Caenorhabditis elegans: Cytoskeletal crosslinkers and beyond.
Fu et al. (2017)
5 more

3 mentions without citation

The Structure of the Plakin Domain of Plectin Reveals an Extended Rod-like Shape.
Ortega et al. (2016)
2 more