› 5j1i

X-ray diffraction
2.8Å resolution

Structure of the spectrin repeats 7, 8, and 9 of the plakin domain of plectin

Released:
DOI: 10.2210/pdb5j1i/pdb
PDB entry 5j1i coloured by chain, front view.
PDB entry 5j1i coloured by chain, side view.
PDB entry 5j1i coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The Structure of the Plakin Domain of Plectin Reveals an Extended Rod-like Shape.
Ortega E, Manso JA, Buey RM, Carballido AM, Carabias A, Sonnenberg A, de Pereda JM
J Biol Chem 291 18643-62 (2016)
PMID: 27413182

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172226 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plectin Chains: A, B
Molecule details ›
Chains: A, B
Length: 373 amino acids
Theoretical weight: 42.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15149 (Residues: 1114-1482; Coverage: 8%)
Gene names: PLEC, PLEC1
Sequence domains: Spectrin repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: C2
Unit cell:
a: 75.24Å b: 90.7Å c: 154.54Å
α: 90° β: 99.13° γ: 90°
R-values:
R R work R free
0.297 0.296 0.322
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

The role of MACF1 in nervous system development and maintenance.
Moffat et al. (2017)
5 more

1 mention without citation

The Structure of the Plakin Domain of Plectin Reveals an Extended Rod-like Shape.
Ortega et al. (2016)