› 5j6z

Solution NMR

Structure of anastellin bound to beta-strands A and B from the third type III domain of fibronectin

Released:
DOI: 10.2210/pdb5j6z/pdb
PDB entry 5j6z coloured by chain, ensemble of 19 models, front view.
PDB entry 5j6z coloured by chain, ensemble of 19 models, side view.
PDB entry 5j6z coloured by chain, ensemble of 19 models, top view.
Source organism: Homo sapiens
Primary publication:
The Interaction between the Third Type III Domain from Fibronectin and Anastellin Involves β-Strand Exchange.
Stine JM, Ahl GJH, Schlenker C, Rusnac DV, Briknarová K
Biochemistry 56 4667-4675 (2017)
PMID: 28820240

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136133 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ugl-Y3 Chain: A
Molecule details ›
Chain: A
Length: 30 amino acids
Theoretical weight: 3.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02751 (Residues: 806-834; Coverage: 1%)
Gene names: FN, FN1
Anastellin Chain: B
Molecule details ›
Chain: B
Length: 89 amino acids
Theoretical weight: 10.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02751 (Residues: 631-705; Coverage: 3%)
Gene names: FN, FN1
Sequence domains: Fibronectin type III domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin.
He et al. (2020)
2 more

2 mentions without citation

The Interaction between the Third Type III Domain from Fibronectin and Anastellin Involves β-Strand Exchange.
Stine et al. (2017)
1 more