PDB 5jjm structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine

Biochemical function:

not assigned

Biological process:

not assigned

Cellular component:

not assigned

Sequence domains:

Structure analysis Details

Assembly composition:

hetero hexamer (preferred)

PDBe Complex ID:

PDB-CPX-145224 (preferred)

Entry contents:

4 distinct polypeptide molecules

Macromolecules (4 distinct):

Androgen receptor Chains: A, C, D

Molecule details ›

Chains: A, C, D
Length: 252 amino acids
Theoretical weight: 29.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

Canonical: P10275 (Residues: 669-920; Coverage: 27%)

Gene names: AR, DHTR, NR3C4
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Unknown peptide Chains: F, K, L, M

Molecule details ›

Chains: F, K, L, M
Length: 3 amino acids
Theoretical weight: 379 Da
Source organism: Homo sapiens
Expression system: Escherichia coli

Androgen receptor Chain: B

Molecule details ›

Chain: B
Length: 252 amino acids
Theoretical weight: 29.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

Canonical: P10275 (Residues: 669-920; Coverage: 27%)

Gene names: AR, DHTR, NR3C4
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

NEDD8-activating enzyme E1 catalytic subunit Chains: G, H, I, J

Molecule details ›

Chains: G, H, I, J
Length: 8 amino acids
Theoretical weight: 936 Da
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt: