› 5joj

Solution NMR

Calcium-loaded EF-hand domain of L-plastin

Released:
DOI: 10.2210/pdb5joj/pdb
PDB entry 5joj coloured by chain, ensemble of 30 models, front view.
PDB entry 5joj coloured by chain, ensemble of 30 models, side view.
PDB entry 5joj coloured by chain, ensemble of 30 models, top view.
Source organism: Homo sapiens
Primary publication:
The Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling.
Ishida H, Jensen KV, Woodman AG, Hyndman ME, Vogel HJ
Sci Rep 7 40662 (2017)
PMID: 28145401

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146764 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plastin-2 Chain: A
Molecule details ›
Chain: A
Length: 97 amino acids
Theoretical weight: 10.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13796 (Residues: 1-97; Coverage: 16%)
Gene names: LCP1, PLS2
Sequence domains: EF hand

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 36%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Plastin 3 in health and disease: a matter of balance.
Wolff et al. (2021)
4 more

5 mentions without citation

Plastin 3 in X-Linked Osteoporosis: Imbalance of Ca2+-Dependent Regulation Is Equivalent to Protein Loss.
Schwebach et al. (2020)
4 more