Function and Biology Details
Reaction catalysed:
Endonucleolytic cleavage to 5'-phosphomonoester
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Protein argonaute-2 and RNA (preferred)
PDBe Complex ID:
PDB-CPX-193880 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Protein argonaute-2
Molecule details ›
Chain: A
Length: 859 amino acids
Theoretical weight: 97.38 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 859 amino acids
Theoretical weight: 97.38 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q9UKV8 (Residues: 1-859; Coverage: 100%)
Sequence domains:
- N-terminal domain of argonaute
- Argonaute linker 1 domain
- PAZ domain
- Argonaute linker 2 domain
- Mid domain of argonaute
- Piwi domain
