› 5k38

X-ray diffraction
2.05Å resolution

Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain

Released:
DOI: 10.2210/pdb5k38/pdb
PDB entry 5k38 coloured by chain, front view.
PDB entry 5k38 coloured by chain, side view.
PDB entry 5k38 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lu J, Rastinejad F

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156324 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear receptor ROR-gamma Chains: A, B
Molecule details ›
Chains: A, B
Length: 247 amino acids
Theoretical weight: 28.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P51449 (Residues: 265-507; Coverage: 47%)
Gene names: NR1F3, RORC, RORG, RZRG
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P61
Unit cell:
a: 99.346Å b: 99.346Å c: 129.411Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.186 0.185 0.207
Expression system: Escherichia coli BL21(DE3)

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