› 5kaz

X-ray diffraction
1.7Å resolution

Human SH2D1B structure

Released:
DOI: 10.2210/pdb5kaz/pdb
PDB entry 5kaz coloured by chain, front view.
PDB entry 5kaz coloured by chain, side view.
PDB entry 5kaz coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The X-ray Crystallographic Structure of Human EAT2 (SH2D1B).
Taha M, Nezerwa E, Nam HJ
Protein Pept Lett 23 862-866 (2016)
PMID: 27586300

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127152 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SH2 domain-containing protein 1B Chain: A
Molecule details ›
Chain: A
Length: 104 amino acids
Theoretical weight: 12.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O14796 (Residues: 1-104; Coverage: 79%)
Gene names: EAT2, SH2D1B
Sequence domains: SH2 domain
Structure domains: SH2 domain

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: I422
Unit cell:
a: 66.983Å b: 66.983Å c: 105.155Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.189 0.214
Expression system: Escherichia coli BL21

Quick links

Citations

1 citations in other articles

Identification of Susceptibility Genes to Allergic Rhinitis by Gene Expression Data Sets.
Xue et al. (2020)