Function and Biology Details
Reactions catalysed:
ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- WD40 repeat
- Phosphatidylinositol 3-/4-kinase, catalytic domain
- Phosphoinositide 3-kinase, accessory (PIK) domain
- C2 phosphatidylinositol 3-kinase-type domain
- Protein kinase domain
- Phosphatidylinositol 3/4-kinase, conserved site
- C2 domain superfamily
- WD40/YVTN repeat-like-containing domain superfamily
11 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149549 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Phosphatidylinositol 3-kinase VPS34
Molecule details ›
Serine/threonine-protein kinase VPS15
Molecule details ›
Chain: B
Length: 1454 amino acids
Theoretical weight: 166.55 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains: Protein kinase domain
Length: 1454 amino acids
Theoretical weight: 166.55 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical:
P22219 (Residues: 1-1454; Coverage: 100%)
Sequence domains: Protein kinase domain
