› 5ki0

Solution NMR

NMR structure of human antimicrobial peptide KAMP-19

Released:
DOI: 10.2210/pdb5ki0/pdb
PDB entry 5ki0 coloured by chain, ensemble of 10 models, front view.
PDB entry 5ki0 coloured by chain, ensemble of 10 models, side view.
PDB entry 5ki0 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Membrane-Active Epithelial Keratin 6A Fragments (KAMPs) Are Unique Human Antimicrobial Peptides with a Non-αβ Structure.
Lee JT, Wang G, Tam YT, Tam C
Front Microbiol 7 1799 (2016)
PMID: 27891122

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135888 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Keratin, type II cytoskeletal 6A Chain: A
Molecule details ›
Chain: A
Length: 19 amino acids
Theoretical weight: 1.77 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P02538 (Residues: 533-551; Coverage: 3%)
Gene names: K6A, KRT6A, KRT6D

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 78%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

5 review citations

Antimicrobial Peptides: An Update on Classifications and Databases.
Bin Hafeez et al. (2021)
4 more

1 mention without citation

Membrane-Active Epithelial Keratin 6A Fragments (KAMPs) Are Unique Human Antimicrobial Peptides with a Non-αβ Structure.
Lee et al. (2016)