› 5ki9

X-ray diffraction
1.6Å resolution

Crystal structure of human beta-defensin 4 (HBD4)

Released:
DOI: 10.2210/pdb5ki9/pdb
PDB entry 5ki9 coloured by chain, front view.
PDB entry 5ki9 coloured by chain, side view.
PDB entry 5ki9 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Jacek L, Adam P, Marzenam P

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186696 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-defensin 104 Chain: A
Molecule details ›
Chain: A
Length: 43 amino acids
Theoretical weight: 5.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WTQ1 (Residues: 23-65; Coverage: 86%)
Gene names: DEFB104, DEFB104A, DEFB104B, DEFB4
Sequence domains: Beta defensin

Ligands and Environments

2 bound ligands:
Ligand SO4 3 x SO4
Ligand TFA 1 x TFA
1 modified residue:
Ligand MLY 3 x MLY

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P43212
Unit cell:
a: 41.704Å b: 41.704Å c: 52.945Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.23 0.268
Expression system: Escherichia coli

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