› 5kjg

Solution NMR

Connexin 26 G12R mutant NMR structure

Released:
DOI: 10.2210/pdb5kjg/pdb
PDB entry 5kjg coloured by chain, ensemble of 20 models, front view.
PDB entry 5kjg coloured by chain, ensemble of 20 models, side view.
PDB entry 5kjg coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural studies of N-terminal mutants of Connexin 26 and Connexin 32 using (1)H NMR spectroscopy.
Batir Y, Bargiello TA, Dowd TL
Arch Biochem Biophys 608 8-19 (2016)
PMID: 27378082

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151331 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gap junction beta-2 protein Chain: A
Molecule details ›
Chain: A
Length: 23 amino acids
Theoretical weight: 2.47 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P29033 (Residues: 1-22; Coverage: 10%)
Gene name: GJB2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 57%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

4 review citations

Gating of Connexin Channels by transjunctional-voltage: Conformations and models of open and closed states.
Bargiello et al. (2018)
3 more

1 mention without citation

Structural studies of N-terminal mutants of Connexin 26 and Connexin 32 using (1)H NMR spectroscopy.
Batir et al. (2016)