› 5klu

X-ray diffraction
1.99Å resolution

Crystal Structure of a Domain-swapped Dimer of Yeast Iso-1-cytochrome c with omega-undecylenyl-beta-D-maltopyranoside

Released:
DOI: 10.2210/pdb5klu/pdb
PDB entry 5klu coloured by chain, front view.
PDB entry 5klu coloured by chain, side view.
PDB entry 5klu coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Cytochrome c Can Form a Well-Defined Binding Pocket for Hydrocarbons.
McClelland LJ, Steele HB, Whitby FG, Mou TC, Holley D, Ross JB, Sprang SR, Bowler BE
J Am Chem Soc 138 16770-16778 (2016)
PMID: 27990813

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132233 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome c isoform 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 106 amino acids
Theoretical weight: 11.77 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P00044 (Residues: 4-109; Coverage: 97%)
Gene names: CYC1, J1653, YJR048W
Sequence domains: Cytochrome c

Ligands and Environments

3 bound ligands:
Ligand HEC 2 x HEC
Ligand 6UZ 2 x 6UZ
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL14-1
Spacegroup: P21212
Unit cell:
a: 54.489Å b: 61.438Å c: 74.165Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.201 0.256
Expression system: Escherichia coli

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Citations

2 review citations

MOMP, cell suicide as a BCL-2 family business.
Kalkavan et al. (2018)
1 more

1 mention without citation

Cytochrome c Can Form a Well-Defined Binding Pocket for Hydrocarbons.
McClelland et al. (2016)