Function and Biology Details
Reaction catalysed:
NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
homo heptamer (preferred)
Assembly name:
Poly [ADP-ribose] polymerase tankyrase-1 (preferred)
PDBe Complex ID:
PDB-CPX-131880 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Poly [ADP-ribose] polymerase tankyrase-1
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 67 amino acids
Theoretical weight: 7.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: SAM domain (Sterile alpha motif)
Structure domains: Transcription Factor, Ets-1
Length: 67 amino acids
Theoretical weight: 7.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
O95271 (Residues: 1026-1091; Coverage: 5%)
Sequence domains: SAM domain (Sterile alpha motif)
Structure domains: Transcription Factor, Ets-1
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 12.3.1
Spacegroup:
P21
Expression system: Escherichia coli
