› 5ku8

X-ray diffraction
2.22Å resolution

Crystal structure of CK2

Released:
DOI: 10.2210/pdb5ku8/pdb
PDB entry 5ku8 coloured by chain, front view.
PDB entry 5ku8 coloured by chain, side view.
PDB entry 5ku8 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of CK2
Ferguson AD
To be published

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159383 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Casein kinase II subunit alpha Chains: A, B
Molecule details ›
Chains: A, B
Length: 331 amino acids
Theoretical weight: 39.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P68400 (Residues: 2-332; Coverage: 85%)
Gene names: CK2A1, CSNK2A1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand SO4 12 x SO4
Ligand EDO 27 x EDO
Ligand 6XK 2 x 6XK
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P43212
Unit cell:
a: 125.914Å b: 125.914Å c: 124.617Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.183 0.216
Expression system: Escherichia coli

Quick links