› 5l2u

X-ray diffraction
2.28Å resolution

Oligomer crystal structure of CC chemokine 5 (CCL5)

Released:
DOI: 10.2210/pdb5l2u/pdb
PDB entry 5l2u coloured by chain, front view.
PDB entry 5l2u coloured by chain, side view.
PDB entry 5l2u coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Liang W, Wang A, Tang W-J

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146626 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 5 Chains: A, B, C, D, E, F, G, H, I
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I
Length: 65 amino acids
Theoretical weight: 7.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13501 (Residues: 27-91; Coverage: 96%)
Gene names: CCL5, D17S136E, SCYA5
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

3 bound ligands:
Ligand EPE 3 x EPE
Ligand CL 2 x CL
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C222
Unit cell:
a: 121.799Å b: 210.082Å c: 126.718Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.178 0.209
Expression system: Escherichia coli

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