› 5l6x

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF HGSTP1-1 COMPLEXED WITH FERROCENE-GLUTATHIONE CONJUGATE

Released:
DOI: 10.2210/pdb5l6x/pdb
PDB entry 5l6x coloured by chain, front view.
PDB entry 5l6x coloured by chain, side view.
PDB entry 5l6x coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lopez-Jaramillo FJ, Garcia-Fuentes L, Vargas-Berenguel A

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140593 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase P Chains: A, B
Molecule details ›
Chains: A, B
Length: 210 amino acids
Theoretical weight: 23.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09211 (Residues: 1-210; Coverage: 100%)
Gene names: FAEES3, GST3, GSTP1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand AZI 11 x AZI
Ligand 6SG 2 x 6SG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OXFORD DIFFRACTION ENHANCE ULTRA
Spacegroup: C2
Unit cell:
a: 77.023Å b: 89.41Å c: 68.604Å
α: 90° β: 97.816° γ: 90°
R-values:
R R work R free
0.181 0.181 0.213
Expression system: Escherichia coli

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