› 5ljg

X-ray diffraction
1.15Å resolution

Crystal structure of holo human CRBP1

Released:
DOI: 10.2210/pdb5ljg/pdb
PDB entry 5ljg coloured by chain, front view.
PDB entry 5ljg coloured by chain, side view.
PDB entry 5ljg coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and molecular determinants affecting the interaction of retinol with human CRBP1.
Menozzi I, Vallese F, Polverini E, Folli C, Berni R, Zanotti G
J Struct Biol 197 330-339 (2017)
PMID: 28057518

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140657 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinol-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 135 amino acids
Theoretical weight: 15.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P09455 (Residues: 1-135; Coverage: 100%)
Gene names: CRBP1, RBP1
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand PLM 1 x PLM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P212121
Unit cell:
a: 34.34Å b: 48.133Å c: 77.555Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.153 0.152 0.173
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Retinol-binding protein 2 (RBP2): biology and pathobiology.
Blaner et al. (2020)
1 more