› 5ljh

X-ray diffraction
1.52Å resolution

Crystal structure of human apo CRBP1/K40L mutant

Released:
DOI: 10.2210/pdb5ljh/pdb
PDB entry 5ljh coloured by chain, front view.
PDB entry 5ljh coloured by chain, side view.
PDB entry 5ljh coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and molecular determinants affecting the interaction of retinol with human CRBP1.
Menozzi I, Vallese F, Polverini E, Folli C, Berni R, Zanotti G
J Struct Biol 197 330-339 (2017)
PMID: 28057518

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140657 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinol-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 135 amino acids
Theoretical weight: 15.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P09455 (Residues: 1-135; Coverage: 100%)
Gene names: CRBP1, RBP1
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P212121
Unit cell:
a: 34.531Å b: 47.603Å c: 77.944Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.169 0.198
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Retinol-binding protein 2 (RBP2): biology and pathobiology.
Blaner et al. (2020)
1 more