Function and Biology Details
Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
- not assigned
Biological process:
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190591 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tyrosine-protein phosphatase non-receptor type 23
Molecule details ›
Chain: A
Length: 352 amino acids
Theoretical weight: 40.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: ALIX V-shaped domain binding to HIV
Length: 352 amino acids
Theoretical weight: 40.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9H3S7 (Residues: 362-713; Coverage: 22%)
Sequence domains: ALIX V-shaped domain binding to HIV
Ubiquitin-associated protein 1
Molecule details ›
Chain: B
Length: 20 amino acids
Theoretical weight: 2.23 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 20 amino acids
Theoretical weight: 2.23 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: Q9NZ09 (Residues: 261-280; Coverage: 4%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I02
Spacegroup:
P212121
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
