Function and Biology Details
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
OTU domain-containing protein 7B (preferred)
PDBe Complex ID:
PDB-CPX-179711 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
OTU domain-containing protein 7B
Molecule details ›
Chain: A
Length: 318 amino acids
Theoretical weight: 36.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: OTU-like cysteine protease
Length: 318 amino acids
Theoretical weight: 36.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q6GQQ9 (Residues: 129-438; Coverage: 37%)
Sequence domains: OTU-like cysteine protease
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-1
Spacegroup:
P41212
Expression system: Escherichia coli
