› 5ltl

X-ray diffraction
1.45Å resolution

Structure of human chemokine CCL16

Released:
DOI: 10.2210/pdb5ltl/pdb
PDB entry 5ltl coloured by chain, front view.
PDB entry 5ltl coloured by chain, side view.
PDB entry 5ltl coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Weiergraeber OH, Batra-Safferling R, Haenel K, Willbold D

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127490 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 16 Chains: A, B
Molecule details ›
Chains: A, B
Length: 100 amino acids
Theoretical weight: 11.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: O15467 (Residues: 24-120; Coverage: 100%)
Gene names: CCL16, ILINCK, NCC4, SCYA16
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

2 bound ligands:
Ligand NA 1 x NA
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 136.35Å b: 24.59Å c: 37.97Å
α: 90° β: 93.12° γ: 90°
R-values:
R R work R free
0.172 0.17 0.198
Expression system: Escherichia coli K-12

Quick links

Citations

3 mentions without citation

The marriage of chemokines and galectins as functional heterodimers.
von Hundelshausen et al. (2021)
2 more