› 5lve

X-ray diffraction
2Å resolution

STRUCTURE OF THE VARIABLE DOMAIN OF HUMAN IMMUNOGLOBULIN K-4 LIGHT CHAIN LEN

Released:
DOI: 10.2210/pdb5lve/pdb
PDB entry 5lve coloured by chain, front view.
PDB entry 5lve coloured by chain, side view.
PDB entry 5lve coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Change in dimerization mode by removal of a single unsatisfied polar residue located at the interface.
Pokkuluri PR, Cai X, Johnson G, Stevens FJ, Schiffer M
Protein Sci 9 1852-5 (2000)
PMID: 11045631

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-138999 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Immunoglobulin kappa variable 4-1 Chain: A
Molecule details ›
Chain: A
Length: 114 amino acids
Theoretical weight: 12.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P06312 (Residues: 21-121; Coverage: 100%)
Gene name: IGKV4-1
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P6222
Unit cell:
a: 106.3Å b: 106.3Å c: 45.1Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.186 0.186 0.218
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers.
Rossmann et al. (2011)
2 more

3 mentions without citation

Stretching to understand proteins - a survey of the protein data bank.
SuĊ‚kowska et al. (2008)
2 more