Function and Biology Details
Reactions catalysed:
(S)-malate + NAD(+) = oxaloacetate + NADH
3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + NADH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
- Malate dehydrogenase, NAD-dependent, cytosolic
- Malate dehydrogenase, type 2
- Lactate/malate dehydrogenase, C-terminal
- Malate dehydrogenase, active site
- Lactate/malate dehydrogenase, N-terminal
- NAD(P)-binding domain superfamily
- L-lactate/malate dehydrogenase
Structure domains:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Malate dehydrogenase, cytoplasmic (preferred)
PDBe Complex ID:
PDB-CPX-145896 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Malate dehydrogenase, cytoplasmic
Molecule details ›
Chains: A, B
Length: 333 amino acids
Theoretical weight: 36.37 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 333 amino acids
Theoretical weight: 36.37 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli
UniProt:
- Canonical:
P11708 (Residues: 2-334; Coverage: 100%)
Sequence domains:
- lactate/malate dehydrogenase, NAD binding domain
- lactate/malate dehydrogenase, alpha/beta C-terminal domain
