› 5mwx

X-ray diffraction
1.29Å resolution

Galectin-1 in Complex with Ligand JB60

Released:
DOI: 10.2210/pdb5mwx/pdb
PDB entry 5mwx coloured by chain, front view.
PDB entry 5mwx coloured by chain, side view.
PDB entry 5mwx coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Grimm C, Bechold J

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140624 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 133 amino acids
Theoretical weight: 14.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09382 (Residues: 3-135; Coverage: 99%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

3 bound ligands:
Ligand BME 1 x BME
Ligand WYD 2 x WYD
Ligand SO4 1 x SO4
1 modified residue:
Ligand CME 6 x CME

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P212121
Unit cell:
a: 43.26Å b: 58.25Å c: 111.25Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.169 0.205
Expression system: Escherichia coli

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