Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
- Intercellular adhesion molecule
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Intercellular adhesion molecule/vascular cell adhesion molecule
- Intercellular adhesion molecule, N-terminal
- Duffy-antigen binding domain
- Duffy-antigen binding superfamily
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138634 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Erythrocyte membrane protein 1, PfEMP1
Molecule details ›
Chain: A
Length: 488 amino acids
Theoretical weight: 55.52 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
UniProt:
Sequence domains: Duffy binding domain
Length: 488 amino acids
Theoretical weight: 55.52 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
UniProt:
- Canonical:
Q8IHM0 (Residues: 728-1214; Coverage: 16%)
Sequence domains: Duffy binding domain
Intercellular adhesion molecule 1
Molecule details ›
Chain: B
Length: 186 amino acids
Theoretical weight: 20.5 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Intercellular adhesion molecule (ICAM), N-terminal domain
Structure domains: Immunoglobulins
Length: 186 amino acids
Theoretical weight: 20.5 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P05362 (Residues: 28-212; Coverage: 37%)
Sequence domains: Intercellular adhesion molecule (ICAM), N-terminal domain
Structure domains: Immunoglobulins
