5n5n

Electron Microscopy
4Å resolution

Cryo-EM structure of tsA201 cell alpha1B and betaI and betaIVb microtubules

Released:
Source organism: Homo sapiens
Primary publication:
Tubulin isoform composition tunes microtubule dynamics.
Mol Biol Cell 28 3564-3572 (2017)
PMID: 29021343
Related structures: EMD-3589

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-139592 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tubulin beta chain Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 426 amino acids
Theoretical weight: 47.74 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P07437 (Residues: 1-426; Coverage: 96%)
Gene names: OK/SW-cl.56, TUBB, TUBB5
Sequence domains:
Structure domains:
Tubulin alpha-1B chain Chains: G, H, I, J, K, L
Molecule details ›
Chains: G, H, I, J, K, L
Length: 437 amino acids
Theoretical weight: 48.67 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P68363 (Residues: 1-437; Coverage: 97%)
Gene name: TUBA1B
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-3589
Expression system: Homo sapiens