› 5n9p

X-ray diffraction
1.8Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-166020 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein enabled homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 113 amino acids
Theoretical weight: 12.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8N8S7 (Residues: 1-111; Coverage: 19%)
Gene names: ENAH, MENA
Sequence domains: WH1 domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Ac-[2-Cl-F]-PP-[ProM-1]-NH2 Chains: C, D, E
Molecule details ›
Chains: C, D, E
Length: 6 amino acids
Theoretical weight: 636 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P3121
Unit cell:
a: 47.266Å b: 47.266Å c: 202.722Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.204 0.203 0.227
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

Quick links

Citations

4 review citations

Migration and homeostasis of regulatory T cells in rheumatoid arthritis.
Kotschenreuther et al. (2022)
3 more