› 5naj

X-ray diffraction
1.46Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185438 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein enabled homolog Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 113 amino acids
Theoretical weight: 12.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: Q8N8S7 (Residues: 1-111; Coverage: 19%)
Gene names: ENAH, MENA
Sequence domains: WH1 domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

4 bound ligands:
Ligand 8SE 4 x 8SE
Ligand SO4 9 x SO4
Ligand 8SB 1 x 8SB
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P21212
Unit cell:
a: 77.954Å b: 80.766Å c: 73.63Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.179 0.2
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'

Quick links

Citations

4 review citations

Migration and homeostasis of regulatory T cells in rheumatoid arthritis.
Kotschenreuther et al. (2022)
3 more