5neg

X-ray diffraction
1.29Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-185441 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein enabled homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 113 amino acids
Theoretical weight: 12.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: Q8N8S7 (Residues: 1-111; Coverage: 19%)
Gene names: ENAH, MENA
Sequence domains: WH1 domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P2
Unit cell:
a: 34.81Å b: 44.36Å c: 72.47Å
α: 90° β: 96.56° γ: 90°
R-values:
R R work R free
0.155 0.153 0.19
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'