Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Cullin-3 and Kelch-like ECH-associated protein 1 (preferred)
PDBe Complex ID:
PDB-CPX-171783 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Kelch-like ECH-associated protein 1
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 17.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: BTB/POZ domain
Length: 154 amino acids
Theoretical weight: 17.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q14145 (Residues: 51-204; Coverage: 25%)
Sequence domains: BTB/POZ domain
Cullin-3
Molecule details ›
Chain: B
Length: 356 amino acids
Theoretical weight: 41.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Cullin family
Structure domains: Cullin Repeats
Length: 356 amino acids
Theoretical weight: 41.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q13618 (Residues: 26-381; Coverage: 46%)
Sequence domains: Cullin family
Structure domains: Cullin Repeats
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I03
Spacegroup:
C2221
Expression system: Escherichia coli
