› 5nnm

X-ray diffraction
1.9Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156080 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Antibacterial peptide LL-37 Chains: A, B
Molecule details ›
Chains: A, B
Length: 37 amino acids
Theoretical weight: 4.5 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P49913 (Residues: 134-170; Coverage: 26%)
Gene names: CAMP, CAP18, FALL39, HSD26
Sequence domains: LPS binding domain of CAP18 (C terminal)

Ligands and Environments

1 bound ligand:
Ligand CO3 4 x CO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P3121
Unit cell:
a: 44.577Å b: 44.577Å c: 87.847Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.225 0.223 0.251
Expression system: Not provided

Quick links

Citations

6 review citations

Atomic-Resolution Structures and Mode of Action of Clinically Relevant Antimicrobial Peptides.
Bhattacharjya et al. (2022)
5 more

4 mentions without citation

Structural Plasticity of LL-37 Indicates Elaborate Functional Adaptation Mechanisms to Bacterial Target Structures.
Zeth et al. (2021)
3 more