5nnx

X-ray diffraction
3.29Å resolution

TEAD1 bound to DNA

Released:
Source organism: Homo sapiens
Entry authors: Morgunova E, Jolma A, Yin Y, Popov A, Taipale J

Function and Biology Details

Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-119066 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Transcriptional enhancer factor TEF-1 Chain: A
Molecule details ›
Chain: A
Length: 74 amino acids
Theoretical weight: 8.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P28347 (Residues: 31-104; Coverage: 17%)
Gene names: TCF13, TEAD1, TEF1
Sequence domains: TEA/ATTS domain
DNA Chain: C
Molecule details ›
Chain: C
Length: 18 nucleotides
Theoretical weight: 5.41 KDa
Source organism: Homo sapiens
Expression system: Not provided
DNA Chain: F
Molecule details ›
Chain: F
Length: 18 nucleotides
Theoretical weight: 5.62 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: R32
Unit cell:
a: 112.3Å b: 112.3Å c: 157.562Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.203 0.196 0.278
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided