5nqc

X-ray diffraction
2Å resolution

CK2alpha in complex with NMR154

Released:
Source organism: Homo sapiens
Entry authors: Seetoh W-G, Stubbs CJ

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-159383 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Casein kinase II subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 334 amino acids
Theoretical weight: 39.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P68400 (Residues: 2-335; Coverage: 85%)
Gene names: CK2A1, CSNK2A1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: P43212
Unit cell:
a: 71.477Å b: 71.477Å c: 126.266Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.196 0.247
Expression system: Escherichia coli