Function and Biology Details
Reaction catalysed:
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154572 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear receptor coactivator 1
Molecule details ›
Chain: A
Length: 132 amino acids
Theoretical weight: 14.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: PAS domain
Structure domains: PAS domain
Length: 132 amino acids
Theoretical weight: 14.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q15788 (Residues: 257-385; Coverage: 9%)
Sequence domains: PAS domain
Structure domains: PAS domain
Signal transducer and activator of transcription 6
Molecule details ›
Chain: B
Length: 32 amino acids
Theoretical weight: 3.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Length: 32 amino acids
Theoretical weight: 3.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P42226 (Residues: 783-814; Coverage: 4%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
88%
Refinement method:
simulated annealing
Expression system: Escherichia coli
