› 5o5i

X-ray diffraction
3.01Å resolution

Robo1 Ig5

Released:
DOI: 10.2210/pdb5o5i/pdb
PDB entry 5o5i coloured by chain, front view.
PDB entry 5o5i coloured by chain, side view.
PDB entry 5o5i coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Robo1 Forms a Compact Dimer-of-Dimers Assembly.
Aleksandrova N, Gutsche I, Kandiah E, Avilov SV, Petoukhov MV, Seiradake E, McCarthy AA
Structure 26 320-328.e4 (2018)
PMID: 29307485

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195377 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Roundabout homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 92 amino acids
Theoretical weight: 9.81 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9Y6N7 (Residues: 454-543; Coverage: 6%)
Gene names: DUTT1, ROBO1
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P61
Unit cell:
a: 80.82Å b: 80.82Å c: 26.83Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.193 0.245
Expression system: Homo sapiens

Quick links

Citations

5 review citations

The Role of the Slit/Robo Signaling Pathway.
Tong et al. (2019)
4 more

4 mentions without citation

An expanded benchmark for antibody-antigen docking and affinity prediction reveals insights into antibody recognition determinants.
Guest et al. (2021)
3 more