› 5oaz

X-ray diffraction
1.03Å resolution

Crystal structure of the Abl-SH3 domain at pH 7.5

Released:
DOI: 10.2210/pdb5oaz/pdb
PDB entry 5oaz coloured by chain, front view.
PDB entry 5oaz coloured by chain, side view.
PDB entry 5oaz coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Camara-Artigas A

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132602 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase ABL1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 63 amino acids
Theoretical weight: 7.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P00519 (Residues: 60-121; Coverage: 6%)
Gene names: ABL, ABL1, JTK7
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

1 bound ligand:
Ligand PEG 3 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P32
Unit cell:
a: 49.919Å b: 49.919Å c: 45.046Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.146 0.145 0.163
Expression system: Escherichia coli BL21(DE3)

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