› 5odd

Solution NMR

HUMAN MED26 N-TERMINAL DOMAIN (1-92)

Released:
DOI: 10.2210/pdb5odd/pdb
PDB entry 5odd coloured by chain, ensemble of 20 models, front view.
PDB entry 5odd coloured by chain, ensemble of 20 models, side view.
PDB entry 5odd coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
1H, 15N and 13C assignments of the N-terminal domain of the Mediator complex subunit MED26.
Peruzzini R, Lens Z, Verger A, Dewitte F, Ferreira E, Baert JL, Villeret V, Landrieu I, Cantrelle FX
Biomol NMR Assign 10 233-6 (2016)
PMID: 26861138

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131921 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mediator of RNA polymerase II transcription subunit 26 Chain: A
Molecule details ›
Chain: A
Length: 92 amino acids
Theoretical weight: 10.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O95402 (Residues: 1-92; Coverage: 15%)
Gene names: ARC70, CRSP7, MED26
Sequence domains: TFIIS helical bundle-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 81%
Refinement method: molecular dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 citations in other articles

A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Cermakova et al. (2021)

1 mention without citation

Twenty years of Mediator complex structural studies.
Verger et al. (2019)