› 5omp

X-ray diffraction
1.88Å resolution

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171693 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase FKBP5 Chain: A
Molecule details ›
Chain: A
Length: 462 amino acids
Theoretical weight: 51.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13451 (Residues: 1-457; Coverage: 100%)
Gene names: AIG6, FKBP5, FKBP51
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P3221
Unit cell:
a: 90.732Å b: 90.732Å c: 133.596Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.198 0.247
Expression system: Escherichia coli

Quick links

Citations

4 review citations

The Many Faces of FKBP51.
Hähle et al. (2019)
3 more

5 mentions without citation

FKBP Ligands-Where We Are and Where to Go?
Kolos et al. (2018)
4 more