› 5oyl

X-ray diffraction
2.25Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-110609 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Glycoprotein Chain: A
Molecule details ›
Chain: A
Length: 410 amino acids
Theoretical weight: 46.1 KDa
Source organism: Recombinant vesicular stomatitis Indiana virus rVSV-G/GFP
UniProt:
  • Canonical: B7UCZ5 (Residues: 17-426; Coverage: 80%)
Gene name: G
Sequence domains: Rhabdovirus spike glycoprotein
Low-density lipoprotein receptor Chain: D
Molecule details ›
Chain: D
Length: 46 amino acids
Theoretical weight: 4.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01130 (Residues: 65-106; Coverage: 5%)
Gene name: LDLR
Sequence domains: Low-density lipoprotein receptor domain class A
Structure domains: Low-density Lipoprotein Receptor

Ligands and Environments

3 bound ligands:
Ligand NAG 3 x NAG
Ligand CA 2 x CA
Ligand GOL 7 x GOL
1 modified residue:
Ligand MLZ 1 x MLZ

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: R32
Unit cell:
a: 90.04Å b: 90.04Å c: 515.78Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.19 0.188 0.224
Expression system: Escherichia coli

Quick links

Citations

16 review citations

Large Clostridial Toxins: Mechanisms and Roles in Disease.
Orrell et al. (2021)
15 more

6 mentions without citation

Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein.
Nikolic et al. (2018)
5 more