› 5t1h

X-ray diffraction
2.11Å resolution

Crystal structure of CK2

Released:
DOI: 10.2210/pdb5t1h/pdb
PDB entry 5t1h coloured by chain, front view.
PDB entry 5t1h coloured by chain, side view.
PDB entry 5t1h coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Feguson AD

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-159383 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Casein kinase II subunit alpha Chains: A, B
Molecule details ›
Chains: A, B
Length: 333 amino acids
Theoretical weight: 39.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P68400 (Residues: 1-333; Coverage: 85%)
Gene names: CK2A1, CSNK2A1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand SO4 13 x SO4
Ligand EDO 26 x EDO
Ligand 75E 2 x 75E
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P43212
Unit cell:
a: 127.09Å b: 127.09Å c: 124.74Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.178 0.203
Expression system: Escherichia coli

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